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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
COG3
All Species:
32.73
Human Site:
Y324
Identified Species:
60
UniProt:
Q96JB2
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96JB2
NP_113619.1
828
94096
Y324
R
S
E
K
I
P
E
Y
Q
Q
L
L
N
D
I
Chimpanzee
Pan troglodytes
XP_001158886
790
89707
Y324
R
S
E
K
I
P
E
Y
Q
Q
L
L
N
D
I
Rhesus Macaque
Macaca mulatta
XP_001096875
828
94056
Y324
R
S
E
K
I
P
E
Y
Q
Q
L
L
N
D
I
Dog
Lupus familis
XP_848489
830
94828
Y326
R
S
E
K
I
P
E
Y
Q
Q
L
L
N
D
I
Cat
Felis silvestris
Mouse
Mus musculus
Q8CI04
820
93264
Y316
R
S
E
K
I
P
E
Y
Q
H
L
L
N
D
I
Rat
Rattus norvegicus
NP_001012157
828
94228
Y324
R
S
E
K
I
P
E
Y
Q
H
L
L
N
D
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_417041
835
94848
Y321
R
S
E
K
M
P
E
Y
Q
Q
V
L
N
E
I
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001137512
820
93798
Y323
R
S
E
K
I
P
E
Y
H
Q
L
L
E
E
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q961G1
905
101221
S311
A
Q
L
I
E
S
R
S
E
H
S
L
D
Y
A
Honey Bee
Apis mellifera
XP_393867
799
92557
S295
Q
E
Y
D
S
L
L
S
E
C
H
Q
C
Y
W
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001196648
781
87158
S311
K
H
A
R
D
H
C
S
L
V
R
S
G
C
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_177485
784
88591
A310
E
E
I
E
S
R
S
A
R
K
E
Y
V
Q
I
Baker's Yeast
Sacchar. cerevisiae
P40094
801
92526
N301
S
I
L
Y
E
C
F
N
H
Y
F
Q
T
R
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.2
98.9
95
N.A.
94.9
96.2
N.A.
N.A.
86.4
N.A.
77
N.A.
40.2
41.5
N.A.
47.5
Protein Similarity:
100
95.4
99.7
97.1
N.A.
96.9
98.1
N.A.
N.A.
92.5
N.A.
87
N.A.
56.4
60.5
N.A.
63.1
P-Site Identity:
100
100
100
100
N.A.
93.3
93.3
N.A.
N.A.
80
N.A.
80
N.A.
6.6
0
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
93.3
93.3
N.A.
N.A.
100
N.A.
86.6
N.A.
20
13.3
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
35.7
21.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
54.8
43
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
8
0
0
0
0
8
0
0
0
0
0
0
16
% A
% Cys:
0
0
0
0
0
8
8
0
0
8
0
0
8
8
0
% C
% Asp:
0
0
0
8
8
0
0
0
0
0
0
0
8
47
0
% D
% Glu:
8
16
62
8
16
0
62
0
16
0
8
0
8
16
0
% E
% Phe:
0
0
0
0
0
0
8
0
0
0
8
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% G
% His:
0
8
0
0
0
8
0
0
16
24
8
0
0
0
0
% H
% Ile:
0
8
8
8
54
0
0
0
0
0
0
0
0
0
70
% I
% Lys:
8
0
0
62
0
0
0
0
0
8
0
0
0
0
0
% K
% Leu:
0
0
16
0
0
8
8
0
8
0
54
70
0
0
8
% L
% Met:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
8
0
0
0
0
54
0
0
% N
% Pro:
0
0
0
0
0
62
0
0
0
0
0
0
0
0
0
% P
% Gln:
8
8
0
0
0
0
0
0
54
47
0
16
0
8
0
% Q
% Arg:
62
0
0
8
0
8
8
0
8
0
8
0
0
8
0
% R
% Ser:
8
62
0
0
16
8
8
24
0
0
8
8
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
8
8
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% W
% Tyr:
0
0
8
8
0
0
0
62
0
8
0
8
0
16
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _